4-Chloro-8-methoxy-2-methylquinoline → (3-Chloro-4-trifluoromethylbenzyl)-(8-methoxy-2-methylquinolin-4-yl)-amine
Reaction equation
Cl[C:2]1[C:11]2[C:6](=[C:7]([O:12][CH3:13])[CH:8]=[CH:9][CH:10]=2)[N:5]=[C:4]([CH3:14])[CH:3]=1.[Cl:15][C:16]1[CH:17]=[C:18]([CH:21]=[CH:22][C:23]=1[C:24]([F:27])([F:26])[F:25])[CH2:19][NH2:20]>>[Cl:15][C:16]1[CH:17]=[C:18]([CH:21]=[CH:22][C:23]=1[C:24]([F:25])([F:26])[F:27])[CH2:19][NH:20][C:2]1[C:11]2[C:6](=[C:7]([O:12][CH3:13])[CH:8]=[CH:9][CH:10]=2)[N:5]=[C:4]([CH3:14])[CH:3]=1Participants
3
Procedure
Preparation was made using a similar procedure as described in example 1, method 1.3. Starting materials were 4-chloro-8-methoxy-2-methylquinoline and 3-chloro-4-trifluoromethylbenzylamine.
Workup
- customPreparation
Sources & evidence
- ORD record
- ord-a61f91a9041c43a0bd8ff74eaf1f5acc