3,4-Difluorobenzylamine → HCID 59474765, compound

Reaction equation

Cl[C:2]1[C:11]2[C:6](=[C:7]([S:12][CH3:13])[CH:8]=[CH:9][CH:10]=2)[N:5]=[C:4]([CH3:14])[CH:3]=1.[F:15][C:16]1[CH:17]=[C:18]([CH:21]=[CH:22][C:23]=1[F:24])[CH2:19][NH2:20]>>[F:15][C:16]1[CH:17]=[C:18]([CH:21]=[CH:22][C:23]=1[F:24])[CH2:19][NH:20][C:2]1[C:11]2[C:6](=[C:7]([S:12][CH3:13])[CH:8]=[CH:9][CH:10]=2)[N:5]=[C:4]([CH3:14])[CH:3]=1

Participants

Reactant 2

HCID 1235723,4-Difluorobenzylamine

HCID 2331984-Chloro-2-methyl-8-methylsulfanylquinoline

Product 1

HCID 59474765HCID 59474765, compound

Procedure

Preparation was made using a similar procedure as described in example 1, method 1.3. Starting materials were 4-chloro-2-methyl-8-methylsulfanylquinoline and 3,4-difluorobenzylamine.

Workup

customPreparation

Sources & evidence

ORD record: ord-460f049ed71b45bfa7d954d257a01336
Source dataset: uspto-grants-2013_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08420670B2

Reaction notes

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