Aniline → N-Phenyl-3-(1-piperidinylsulfonyl)benzamide

Reaction equation

[N:1]1([S:7]([C:10]2[CH:11]=[C:12]([CH:16]=[CH:17][CH:18]=2)[C:13]([OH:15])=O)(=[O:9])=[O:8])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[NH2:19][C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1>>[C:20]1([NH:19][C:13](=[O:15])[C:12]2[CH:16]=[CH:17][CH:18]=[C:10]([S:7]([N:1]3[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]3)(=[O:8])=[O:9])[CH:11]=2)[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1

Participants

Reactant 2

HCID 6115Aniline

HCID 7678893-(Piperidine-1-sulfonyl)benzoic acid

Product 1

HCID 558837N-Phenyl-3-(1-piperidinylsulfonyl)benzamide

Procedure

The entitled compound was produced according to the method of Example 73 but using 3-(piperidin-1-ylsulfonyl)benzoic acid and aniline as the starting materials.

Workup

customThe entitled compound was produced

Sources & evidence

ORD record: ord-dc9fcdd427f2482d99f2e0035aa731e8
Source dataset: uspto-grants-2013_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08420823B2

Reaction notes

Loading…