HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1973178Generated: October 26, 2026
Dimethylamine → Hexahydro-2a,5a,8a-triaza-8b-phospha-acenaphthylene
https://huagongshe.com/reaction/1973178
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Dimethylamine | HCID 674 | — |
| Reactant | Hexamethylphosphorous triamide | HCID 15355 | — |
| Reactant | 1,4,8-Triazacycloundecane | HCID 398742 | — |
| Product | Hexahydro-2a,5a,8a-triaza-8b-phospha-acenaphthylene | HCID 23414755 | 75.2% |
Reaction Steps
A mixture of 3.62 g of 1,4,8-triazacycloundecane and 3.75 g of hexamethylphosphorous triamide is heated to 125° C with stirring and held at this temperature for 2 hours, by which time evolution of dimethylamine is complete. Evolution is vigorous for the first 45 minutes. Distillation affords 3.20 g (75%) 1,4,8-triaza-12-phosphatricyclo-[6.3.1.04,12 ]dodecane as a water-white liquid which boils at 73°-75° C at 0.30 mm.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US03996276 |
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| Source dataset | uspto-grants-1976_12 |
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| ORD ID | ord-b13e99e974744e3a9603d095231b7332 |
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| Source note | uspto-grants-1976_12 |
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