N,N-dimethyl-N-(4-nitrophenyl)carbamylmethyl-N-3-formamidopropylammonium chloride → N,N-dimethyl-N-(4-aminophenyl)carbamylmethyl-N-3-formamidopropylammonium chloride

HRID 1973210Notes

Reaction equation

HRID 1973210 reaction equation
[Cl-:1].[CH3:2][N+:3]([CH3:23])([CH2:10][C:11](=[O:22])[NH:12][C:13]1[CH:18]=[CH:17][C:16]([N+:19]([O-])=O)=[CH:15][CH:14]=1)[CH2:4][CH2:5][CH2:6][NH:7][CH:8]=[O:9]>[Pt]=S>[Cl-:1].[CH3:23][N+:3]([CH3:2])([CH2:10][C:11](=[O:22])[NH:12][C:13]1[CH:18]=[CH:17][C:16]([NH2:19])=[CH:15][CH:14]=1)[CH2:4][CH2:5][CH2:6][NH:7][CH:8]=[O:9]

Participants

3

Reactant 1

HCID 86733006N,N-dimethyl-N-(4-nitrophenyl)carbamylmethyl-N-3-formamidopropylammonium chloride

Product 1

HCID 86733008N,N-dimethyl-N-(4-aminophenyl)carbamylmethyl-N-3-formamidopropylammonium chloride

Reagents, catalysts & solvents 1

HCID 82861Platinum sulfide (PtS)Catalyst

Procedure

Following the procedure described in 1c above, N,N-dimethyl-N-(4-nitrophenyl)carbamylmethyl-N-3-formamidopropylammonium chloride was catalytically hydrogenated in aqueous solution at 70°-75° C. and at 600 pounds per square inch in the presence of a 5 percent platinum sulfide on charcoal mixture to obtain N,N-dimethyl-N-(4-aminophenyl)carbamylmethyl-N-3-formamidopropylammonium chloride.

Sources & evidence

ORD record
ord-c9e8b65a72f54e6faf8bfcefa6d0b058
Source dataset
uspto-grants-1976_12
Patent number
US03996282

Reaction notes

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