N-(2-{[(2-Amino-1,3-thiazol-4-yl)methyl]sulfanyl}ethyl)-N'-methylthiourea → HCID 178484987, compound

Reaction equation

[CH3:1][NH:2][C:3]([NH:5][CH2:6][CH2:7][S:8][CH2:9][C:10]1[N:11]=[C:12]([NH2:15])[S:13][CH:14]=1)=S.[N:16]#[C:17][NH2:18].[Pb]>>[C:17]([NH:18][C:3]([NH:2][CH3:1])=[N:5][CH2:6][CH2:7][S:8][CH2:9][C:10]1[N:11]=[C:12]([NH2:15])[S:13][CH:14]=1)#[N:16]

Participants

Reactant 2

HCID 12923383N-(2-{[(2-Amino-1,3-thiazol-4-yl)methyl]sulfanyl}ethyl)-N'-methylthiourea

HCID 22262466CH2N2Pb

Product 1

HCID 178484987HCID 178484987, compound

Procedure

Reaction of N-methyl-N'-[2-((2-amino-4-thiazolyl)-methylthio)ethyl]thiourea with lead cyanamide by the procedure of Example 91, refluxing for 24 hours, gives the title compound.

Workup

temperaturerefluxing for 24 hours

Sources & evidence

ORD record: ord-3eff1b04cd64435ea9cb0d93a3d93f0e
Source dataset: uspto-grants-1976_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04000302

Reaction notes

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