2-Butenoic acid, ethyl ester → Ethyl 3-(4-amino-2-chlorophenyl)but-2-enoate

HRID 197653

Reaction equation

HRID 197653 reaction equation
[Br:1][c:2]1[c:3]([Cl:9])[cH:4][c:5]([NH2:6])[cH:7][cH:8]1.[C:10]([CH:11]=[CH:12][CH3:13])(=[O:14])[O:15][CH2:16][CH3:17].[NH2:18][c:19]1[c:20]([F:21])[cH:22][c:23]([C:24]([CH3:25])=[CH:26][C:27]([O:28][CH2:29][CH3:30])=[O:31])[c:32]([F:33])[cH:34]1>>[c:2]1([C:12](=[CH:11][C:10](=[O:14])[O:15][CH2:16][CH3:17])[CH3:13])[c:3]([Cl:9])[cH:4][c:5]([NH2:6])[cH:7][cH:8]1

Participants

4

Reactant 3

HCID 121912-Butenoic acid, ethyl esterHCID 888884-Bromo-3-chloroanilineHCID 91038933Ethyl 3-(4-amino-2,5-difluorophenyl)but-2-enoate

Product 1

HCID 91297204Ethyl 3-(4-amino-2-chlorophenyl)but-2-enoate

Sources & evidence

ORD record
ord-5f205ad33d8d46fb9c505d8d447a04f1
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Linked notes

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