3-(Chloromethyl)-5-[2-fluoro-5-(trifluoromethyl)phenyl]-1,2,4-oxadiazole → 2-Cyclopropyl-1-({5-[2-fluoro-5-(trifluoromethyl)phenyl]-1,2,4-oxadiazol-3-yl}methyl)-4-(trifluoromethyl)-1H-indole-5-carbonitrile

HRID 197716

Reaction equation

HRID 197716 reaction equation
[CH:1]1([c:4]2[nH:5][c:6]3[cH:7][cH:8][c:9]([C:17]#[N:18])[c:10]([C:13]([F:14])([F:15])[F:16])[c:11]3[cH:12]2)[CH2:2][CH2:3]1.[Cl:19][CH2:20][c:21]1[n:22][o:23][c:24](-[c:26]2[c:27]([F:36])[cH:28][cH:29][c:30]([C:32]([F:33])([F:34])[F:35])[cH:31]2)[n:25]1>>[CH:1]1([c:4]2[n:5]([CH2:20][c:21]3[n:22][o:23][c:24](-[c:26]4[c:27]([F:36])[cH:28][cH:29][c:30]([C:32]([F:33])([F:34])[F:35])[cH:31]4)[n:25]3)[c:6]3[cH:7][cH:8][c:9]([C:17]#[N:18])[c:10]([C:13]([F:14])([F:15])[F:16])[c:11]3[cH:12]2)[CH2:2][CH2:3]1

Participants

3

Reactant 2

HCID 53117343-(Chloromethyl)-5-[2-fluoro-5-(trifluoromethyl)phenyl]-1,2,4-oxadiazoleHCID 674044722-cyclopropyl-4-(trifluoromethyl)-1H-indole-5-carbonitrile

Product 1

HCID 866207222-Cyclopropyl-1-({5-[2-fluoro-5-(trifluoromethyl)phenyl]-1,2,4-oxadiazol-3-yl}methyl)-4-(trifluoromethyl)-1H-indole-5-carbonitrile

Sources & evidence

ORD record
ord-77c8c0f89f6c49e89ad9ba0a6fbf16c9
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Linked notes

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