1,3,5,7-Tetrahydroxyadamantane → 1,3,5-Trihydroxy-7-acryloyloxyadamantane

HRID 1978120

Reaction equation

HRID 1978120 reaction equation
[C:1](OCC12CC3CC(CC(O)(C3)C1)C2)(=[O:4])[CH:2]=[CH2:3].[OH:18][C:19]12[CH2:29][C:23]3([OH:30])[CH2:24][C:25]([OH:28])([CH2:27][C:21]([OH:31])([CH2:22]3)[CH2:20]1)[CH2:26]2>>[OH:18][C:19]12[CH2:20][C:21]3([OH:31])[CH2:22][C:23]([O:30][C:1](=[O:4])[CH:2]=[CH2:3])([CH2:24][C:25]([OH:28])([CH2:27]3)[CH2:26]1)[CH2:29]2

Participants

3

Reactant 2

HCID 8200931,3,5,7-TetrahydroxyadamantaneHCID 219967831-Hydroxy-3-(acryloyloxymethyl)adamantane

Product 1

HCID 219967901,3,5-Trihydroxy-7-acryloyloxyadamantaneYield 83%

Procedure

The reaction was conducted in the same manner as the step of Example 36 (2) except that 1,3,5,7-tetrahydroxyadamantane was used instead of the 1,3-dicarboxy-5-adamantanol, and, as a result, a 1,3,5-trihydroxy-7-acryloyloxyadamantane (yield: 83%, white solid) was obtained.

Sources & evidence

ORD record
ord-40d3d6ff280a48f29989019d35165277
Source dataset
uspto-grants-2001_05
Patent number
US06235851B1

Linked notes

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