1-Hydroxyadamantan-2-one → 1-Acryloyloxyadamantane-2-one

HRID 1978123

Reaction equation

HRID 1978123 reaction equation
[C:1](OCC12CC3CC(CC(O)(C3)C1)C2)(=[O:4])[CH:2]=[CH2:3].[OH:18][C:19]12[CH2:28][CH:23]3[CH2:24][CH:25]([CH2:27][CH:21]([CH2:22]3)[C:20]1=[O:29])[CH2:26]2>>[C:1]([O:18][C:19]12[CH2:26][CH:25]3[CH2:24][CH:23]([CH2:22][CH:21]([CH2:27]3)[C:20]1=[O:29])[CH2:28]2)(=[O:4])[CH:2]=[CH2:3]

Participants

3

Reactant 2

HCID 109648841-Hydroxyadamantan-2-oneHCID 219967831-Hydroxy-3-(acryloyloxymethyl)adamantane

Product 1

HCID 184010791-Acryloyloxyadamantane-2-oneYield 94%

Procedure

The reaction was conducted in the same manner as the step of Example 36 (2) except that 1-hydroxyadamantane-2-one was used instead of the 1,3-dicarboxy-5-adamantanol, and, as a result, a 1-acryloyloxyadamantane-2-one (yield: 94%, white solid) was obtained.

Sources & evidence

ORD record
ord-10f360d5c4f3471eb9fbf03daf2acac3
Source dataset
uspto-grants-2001_05
Patent number
US06235851B1

Linked notes

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