HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanolamine → 2-{[(4-Tert-butylphenyl)methyl]amino}ethan-1-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanolamine | HCID 700 | — |
| Reactant | 4-tert-Butylbenzaldehyde | HCID 70324 | — |
| Reactant | Sodium borohydride | HCID 4311764 | — |
| Product | 2-{[(4-Tert-butylphenyl)methyl]amino}ethan-1-ol | HCID 28833038 | 93% |
Reaction Steps
The title compound was synthesized in analogy to example S3-C using 4-tert-butylbenzaldehyde (1000 mg, 6.17 mmol), ethanolamine (371 μl, 6.17 mmol) and sodium borohydride (350 mg, 9.25 mmol). The desired product (1190 mg, 93%) was isolated without further purification as a colorless oil. MS (ISP) 208.3 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07745477B2 |
| Source dataset | uspto-grants-2010_06 |
| ORD ID | ord-62d199f6d737452d93ec52c8e6f55004 |
| Source note | uspto-grants-2010_06 |