Dichloromethane → N-[2-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-4-fluorophthalimide

Reaction equation

[Cl:32][CH2:33][Cl:34].[F:1][c:2]1[cH:3][c:4]2[c:5]([c:6]([CH:9]3[CH2:10][CH2:11][N:12]([CH2:15][CH2:16][NH2:17])[CH2:13][CH2:14]3)[n:7][o:8]2)[cH:18][cH:19]1.[F:20][c:21]1[cH:22][c:23]2[c:24]([cH:30][cH:31]1)[C:25](=[O:26])[O:27][C:28]2=[O:29]>>[F:1][c:2]1[cH:3][c:4]2[c:5]([c:6]([CH:9]3[CH2:10][CH2:11][N:12]([CH2:15][CH2:16][N:17]4[C:25](=[O:26])[c:24]5[c:23]([cH:22][c:21]([F:20])[cH:31][cH:30]5)[C:28]4=[O:27])[CH2:13][CH2:14]3)[n:7][o:8]2)[cH:18][cH:19]1

Participants

Reactant 3

HCID 6344Dichloromethane

HCID 675721,3-Isobenzofurandione, 5-fluoro-

HCID 146998572-(4-(6-Fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethan-1-amine

Product 1

HCID 15378691N-[2-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-4-fluorophthalimide

Sources & evidence

ORD record: ord-3c6c28059a1348d98b54295c33bfe747
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (6/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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