Methyl iodide → HCID 20437408, compound
Reaction equation
[OH:1][CH:2]([CH2:9][NH:10][S:11]([C:14]1[C:23]2[C:18](=[CH:19][CH:20]=[CH:21][CH:22]=2)[CH:17]=[CH:16][CH:15]=1)(=[O:13])=[O:12])[CH2:3][N:4]1[CH2:8][CH2:7][CH2:6][CH2:5]1.[CH3:24][I:25]>CO>[I-:25].[OH:1][CH:2]([CH2:9][NH:10][S:11]([C:14]1[C:23]2[C:18](=[CH:19][CH:20]=[CH:21][CH:22]=2)[CH:17]=[CH:16][CH:15]=1)(=[O:13])=[O:12])[CH2:3][N+:4]1([CH3:24])[CH2:8][CH2:7][CH2:6][CH2:5]1Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
To a solution of 1-[2-hydroxy-3-(1-naphthalenesulphonamido)propyl]pyrrolidine (2 g; 0.0005 mol) in methanol (50 ml) was added methyl iodide (6.9 g; 0.05 mol). The mixture was left at room temperature 12 hours. The reaction mixture was evaporated to dryness and the residue was recrystallized from ethanol (20 ml) to obtain the product (1.3 g).