Ammonia → Tert-butyl 3-[(2-amino-2-oxoethoxy)-(3-chloro-2-fluorophenyl)methyl]piperidine-1-carboxylate
Reaction equation
[CH3:31][OH:32].[Cl:1][c:2]1[c:3]([F:29])[c:4]([CH:8]([CH:9]2[CH2:10][N:11]([C:15](=[O:16])[O:17][C:18]([CH3:19])([CH3:20])[CH3:21])[CH2:12][CH2:13][CH2:14]2)[O:22][CH2:23][C:24](=[O:25])[O:26][CH2:27][CH3:28])[cH:5][cH:6][cH:7]1.[NH3:30]>>[Cl:1][c:2]1[c:3]([F:29])[c:4]([CH:8]([CH:9]2[CH2:10][N:11]([C:15](=[O:16])[O:17][C:18]([CH3:19])([CH3:20])[CH3:21])[CH2:12][CH2:13][CH2:14]2)[O:22][CH2:23][C:24](=[O:25])[NH2:30])[cH:5][cH:6][cH:7]1Participants
4
Sources & evidence
- ORD record
- ord-6dbfb8c1158d49548daa5228d5fe4469
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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