Ethyl 2-acetamido-3-benzylaminobutyrate → Ethyl 2-acetamido-3-aminobutyrate
Reaction equation
[C:1]([NH:4][CH:5]([CH:11]([NH:13]CC1C=CC=CC=1)[CH3:12])[C:6]([O:8][CH2:9][CH3:10])=[O:7])(=[O:3])[CH3:2].[H][H]>C(O)C.[Pd]>[C:1]([NH:4][CH:5]([CH:11]([NH2:13])[CH3:12])[C:6]([O:8][CH2:9][CH3:10])=[O:7])(=[O:3])[CH3:2]Participants
5
Reactant 2
Product 1
Reagents, catalysts & solvents 2
Procedure
Five grams of ethyl 2-acetamido-3-benzylaminobutyrate were dispersed in 20 ml of ethanol together with 0.5 of 5% palladium-on-carbon and shaken under 40 psi of hydrogen until hydrogen uptake had ceased. The mixture was filtered through Celite and evaporated to give a 100% yield of ethyl 2-acetamido-3-aminobutyrate.
Workup
- filtrationThe mixture was filtered through Celite
- customevaporated
Sources & evidence
- ORD record
- ord-1240d6c20d4641eaaaa2a6f34dded9c5
- Source dataset
- uspto-grants-1986_06
- Patent number
- US04593118
Reaction notes
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