(6-chloro-1H-indol-3-yl)-[4-(2,6-dimethoxy-phenyl)-piperidin-1-yl]-methanone → [6-Chloro-1-(6-chloro-pyridin-3-ylmethyl)-1H-indol-3-yl]-[4-(2,6-dimethoxy-phenyl)-piperidin-1-yl]-methanone

HRID 198192

Reaction equation

HRID 198192 reaction equation
[Cl:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([C:11](=[O:12])[N:13]3[CH2:14][CH2:15][CH:16]([c:19]4[c:20]([O:27][CH3:28])[cH:21][cH:22][cH:23][c:24]4[O:25][CH3:26])[CH2:17][CH2:18]3)[cH:7][nH:8][c:9]2[cH:10]1.[Cl:29][c:30]1[cH:31][cH:32][c:33]([CH2:36][O:37][S:38]([CH3:39])(=[O:40])=[O:41])[cH:34][n:35]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([C:11](=[O:12])[N:13]3[CH2:14][CH2:15][CH:16]([c:19]4[c:20]([O:27][CH3:28])[cH:21][cH:22][cH:23][c:24]4[O:25][CH3:26])[CH2:17][CH2:18]3)[cH:7][n:8]([CH2:36][c:33]3[cH:32][cH:31][c:30]([Cl:29])[n:35][cH:34]3)[c:9]2[cH:10]1

Participants

3

Reactant 2

HCID 16062188(6-chloro-1H-indol-3-yl)-[4-(2,6-dimethoxy-phenyl)-piperidin-1-yl]-methanoneHCID 23020401(6-Chloropyridin-3-yl)methyl methanesulphonate

Product 1

HCID 16062308[6-Chloro-1-(6-chloro-pyridin-3-ylmethyl)-1H-indol-3-yl]-[4-(2,6-dimethoxy-phenyl)-piperidin-1-yl]-methanone

Sources & evidence

ORD record
ord-53bfaf0ab8c34463a668d09426810424
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Linked notes

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