Thionyl Chloride → HCID 23149134, compound
Reaction equation
[F:1][C:2]([F:14])([C:7]1[N:11]=[CH:10][N:9]([CH2:12]O)[N:8]=1)[C:3]([F:6])([F:5])[F:4].S(Cl)([Cl:17])=O>ClCCl>[Cl:17][CH2:12][N:9]1[CH:10]=[N:11][C:7]([C:2]([F:14])([F:1])[C:3]([F:6])([F:5])[F:4])=[N:8]1Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
1.52 g of 3-(pentafluoroethyl)-1H-1,2,4-triazole 1-ylmethanol was dissolved to 50 ml of dichloromethane, and 2.7 ml of thionyl chloride was added to the solution, followed by stirring at room temperature for overnight. The reaction mixture was concentrated under reduced pressure to obtain 1.36 g of 1-(chloromethyl)-3-(pentafluoroethyl)-1H-1,2,4-triazole.
Workup
- additionwas added to the solution
- concentrationThe reaction mixture was concentrated under reduced pressure
Sources & evidence
- ORD record
- ord-f551d250f7b5451899a0a35fc0cf192b
- Source dataset
- uspto-grants-2009_06
- Patent number
- US07541374B2
Reaction notes
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