3-Methoxyphenyl isocyanate → Dimethyl 2-[4-ethoxy-3-({[(3-methoxyanilino)carbonyl]oxy}methyl)benzyl]malonate

HRID 1985375

Reaction equation

HRID 1985375 reaction equation
[CH2:1]([O:3][C:4]1[CH:19]=[CH:18][C:7]([CH2:8][CH:9]([C:14]([O:16][CH3:17])=[O:15])[C:10]([O:12][CH3:13])=[O:11])=[CH:6][C:5]=1[CH2:20][OH:21])[CH3:2].[CH3:22][O:23][C:24]1[CH:25]=[C:26]([N:30]=[C:31]=[O:32])[CH:27]=[CH:28][CH:29]=1>>[CH2:1]([O:3][C:4]1[CH:19]=[CH:18][C:7]([CH2:8][CH:9]([C:14]([O:16][CH3:17])=[O:15])[C:10]([O:12][CH3:13])=[O:11])=[CH:6][C:5]=1[CH2:20][O:21][C:31]([NH:30][C:26]1[CH:27]=[CH:28][CH:29]=[C:24]([O:23][CH3:22])[CH:25]=1)=[O:32])[CH3:2]

Participants

3

Reactant 2

HCID 878433-Methoxyphenyl isocyanateHCID 22926717Dimethyl 2-[4-ethoxy-3-(hydroxymethyl)benzyl]malonate

Product 1

HCID 57719590Dimethyl 2-[4-ethoxy-3-({[(3-methoxyanilino)carbonyl]oxy}methyl)benzyl]malonate

Procedure

Using dimethyl 2-[4-ethoxy-3-(hydroxymethyl)benzyl]-malonate and 3-methoxyphenylisocyanate, the title compound was obtained in the same manner as described in Example 192b).

Sources & evidence

ORD record
ord-956abd5df434457987e9af6ffdc9445d
Source dataset
uspto-grants-2009_06
Patent number
US07544835B2

Linked notes

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