3-(4-Isopropyl-piperazin-1-yl)-propylamine → Racemic 4-(3-aminopropyl)-3-isopropylpiperazine-1-carboxylic acid tert-butyl ester

HRID 1986215

Reaction equation

HRID 1986215 reaction equation
C(N1CC[N:7]([CH2:10][CH2:11][CH2:12]N)CC1)(C)C.[C:14]([O:18][C:19]([N:21]1[CH2:26][CH2:25][NH:24][CH:23]([CH:27]([CH3:29])[CH3:28])[CH2:22]1)=[O:20])([CH3:17])([CH3:16])[CH3:15]>>[C:14]([O:18][C:19]([N:21]1[CH2:26][CH2:25][N:24]([CH2:12][CH2:11][CH2:10][NH2:7])[CH:23]([CH:27]([CH3:29])[CH3:28])[CH2:22]1)=[O:20])([CH3:17])([CH3:16])[CH3:15]

Participants

3

Reactant 2

HCID 128029563-(4-Isopropyl-piperazin-1-yl)-propylamineHCID 44558596tert-Butyl 3-(propan-2-yl)piperazine-1-carboxylate

Product 1

HCID 68857982Racemic 4-(3-aminopropyl)-3-isopropylpiperazine-1-carboxylic acid tert-butyl ester

Procedure

Using the method of 3-(4-isopropylpiperazin-1-yl)-propylamine, the title compound is synthesized from racemic 3-isopropyl-piperazine-1-carboxylic acid tert-butyl ester and isolated as a tan oil.

Workup

  1. customisolated as a tan oil

Sources & evidence

ORD record
ord-e4bd8d2117cf4ed4a6762ed5529b98b2
Source dataset
uspto-grants-2009_06
Patent number
US07547691B2

Linked notes

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