Pyrrolidine-2-carboxamide → 1-((6-(1-(Benzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)pyridin-3-yl)(2-methoxyphenyl)methyl)pyrrolidine-2-carboxamide

HRID 199081

Reaction equation

HRID 199081 reaction equation
[CH3:1][S:2]([O:3][CH:6]([c:7]1[c:8]([O:13][CH3:14])[cH:9][cH:10][cH:11][cH:12]1)[c:15]1[cH:16][n:17][c:18]([NH:21][C:22](=[O:23])[C:24]2([c:27]3[cH:28][c:29]4[c:30]([cH:34][cH:35]3)[O:31][CH2:32][O:33]4)[CH2:25][CH2:26]2)[cH:19][cH:20]1)(=[O:4])=[O:5].[NH:36]1[CH:37]([C:41](=[O:42])[NH2:43])[CH2:38][CH2:39][CH2:40]1.[O:44]1[c:45]2[cH:46][cH:47][c:48]([C:49]3([C:50]([NH:51][c:52]4[cH:53][cH:54][c:55]([CH:56]([N:57]([CH3:58])[CH3:59])[c:60]5[cH:61][cH:62][cH:63][cH:64][c:65]5[O:66][CH3:67])[cH:68][n:69]4)=[O:70])[CH2:71][CH2:72]3)[cH:73][c:74]2[O:75][CH2:76]1>>[CH:6]([c:7]1[c:8]([O:13][CH3:14])[cH:9][cH:10][cH:11][cH:12]1)([c:15]1[cH:16][n:17][c:18]([NH:21][C:22](=[O:23])[C:24]2([c:27]3[cH:28][c:29]4[c:30]([cH:34][cH:35]3)[O:31][CH2:32][O:33]4)[CH2:25][CH2:26]2)[cH:19][cH:20]1)[N:36]1[CH:37]([C:41](=[O:42])[NH2:43])[CH2:38][CH2:39][CH2:40]1

Participants

4

Reactant 3

HCID 550774Pyrrolidine-2-carboxamideHCID 442364971-(benzo[d][1,3]dioxol-5-yl)-N-(5-((dimethylamino)(2-methoxyphenyl)methyl)pyridin-2-yl)cyclopropanecarboxamideHCID 57895126(6-(1-(Benzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)pyridin-3-yl)(2-methoxyphenyl)methyl methanesulfonate

Product 1

HCID 578951491-((6-(1-(Benzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)pyridin-3-yl)(2-methoxyphenyl)methyl)pyrrolidine-2-carboxamide

Sources & evidence

ORD record
ord-47df33cf33724723b47298570584b3db
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Linked notes

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