Ethanol → (RS)-6-[4-(tert-butyl-dimethyl-silanyloxy)-2-hydroxy-butylamino]-4H-benzo[1,4]thiazin-3-one

HRID 199085

Reaction equation

HRID 199085 reaction equation
[C:13]([CH3:14])([CH3:15])([CH3:16])[Si:17]([O:18][CH2:19][CH2:20][CH:21]1[O:22][CH2:23]1)([CH3:24])[CH3:25].[CH3:26][CH2:27][OH:28].[NH2:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([cH:12]1)[NH:7][C:8](=[O:11])[CH2:9][S:10]2.[OH2:29]>>[NH:1]([c:2]1[cH:3][cH:4][c:5]2[c:6]([cH:12]1)[NH:7][C:8](=[O:11])[CH2:9][S:10]2)[CH2:23][CH:21]([CH2:20][CH2:19][O:18][Si:17]([C:13]([CH3:14])([CH3:15])[CH3:16])([CH3:24])[CH3:25])[OH:22]

Participants

5

Reactant 4

HCID 702EthanolHCID 962WaterHCID 6869016-amino-3,4-dihydro-2H-1,4-benzothiazin-3-oneHCID 11030897(R)-tert-butyldimethyl(2-(oxiran-2-yl)ethoxy)silane

Product 1

HCID 67222623(RS)-6-[4-(tert-butyl-dimethyl-silanyloxy)-2-hydroxy-butylamino]-4H-benzo[1,4]thiazin-3-one

Sources & evidence

ORD record
ord-d5a3c3332d1f45ad93ab77e01da839eb
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Linked notes

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