Formaldehyde → HCID 20402431, compound
Reaction equation
[CH:1]([NH:4][CH:5]([CH3:11])[CH2:6][O:7][CH:8]([OH:10])[CH3:9])([CH3:3])[CH3:2].[CH2:12]=O>[Pd].CO>[CH:1]([N:4]([CH:5]([CH3:11])[CH2:6][O:7][CH:8]([OH:10])[CH3:9])[CH3:12])([CH3:3])[CH3:2]Participants
5
Reactant 2
Product 1
Reagents, catalysts & solvents 2
Conditions
- Temperature
- 80 °C
Procedure
A total of 155 g of 2-(isopropylamino) propoxyethanol, 122 g of 37% aqueous formaldehyde, 5 g of 10% Pd/C and 1 l of methanol were charged to an autoclave, pressured to 1000 psi with H2 and heated at 80° C. for 3 hours. Filtration and distillation of the reaction mixture yielded 159 g of 2-(N-isopropyl-N-methylamino)propoxyethanol with b.p. of 125° C. at 20 mm.
Workup
- filtrationFiltration and distillation of the reaction mixture
Sources & evidence
- ORD record
- ord-6e7945c5f7b24739a959cda60bcbe050
- Source dataset
- uspto-grants-1983_09
- Patent number
- US04405811
Reaction notes
Loading…