HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-(2-methoxy-4-nitrophenyl)methanesulfonamide → N-(4-amino-2-methoxyphenyl)methanesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-(2-methoxy-4-nitrophenyl)methanesulfonamide | HCID 3298129 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | N-(4-amino-2-methoxyphenyl)methanesulfonamide | HCID 12254686 | — |
Reaction Steps
A solution of 2-methoxy-4-nitro-methanesulfonylaminobenzene (1 g) in methanol (20 ml) containing palladium on carbon (10%, 100 mg) was stirred at RT under hydrogen for 48 h. The mixture was filtered through celite then evaporated to give 2-methoxy-4-amino-methanesulfonylaminobenzene as a brown gum. This was used without purification in the following reaction.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07745490B2 |
| Source dataset | uspto-grants-2010_06 |
| ORD ID | ord-b501c60fe6a048f9828185b27265d697 |
| Source note | uspto-grants-2010_06 |