HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,5-Dibromopentane → 1-(5-Bromopentyl)-7-ethoxymethyl-3-methylxanthine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,5-Dibromopentane | HCID 8100 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 7-Ethoxymethylxanthine | HCID 19689183 | — |
| Product | 1-(5-Bromopentyl)-7-ethoxymethyl-3-methylxanthine | HCID 19689250 | — |
Reaction Steps
22.4 g (0.1 mol) of 7-ethoxymethylxanthine were stirred at 70° C. for 1.5 hours with 45.9 g (0.2 mol) of 1,5-dibromopentane and 27.6 g of activated potassium carbonate. The solution was filtered and concentrated, and the oily residue which remained was chromatographed (eluent: ethyl acetate).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05728686 |
| Source dataset | uspto-grants-1998_03 |
| ORD ID | ord-cebc848bbe99485aaab1cf4393713d41 |
| Source note | uspto-grants-1998_03 |