2,3,7-Tribromo-1-(4-fluoro-benzyl)-4-hydroxy-1H-pyrrolo[2,3-c]pyridine-5-carboxylic acid ethyl ester → 2,3-Dibromo-7-cyano-1-(4-fluoro-benzyl)-4-hydroxy-1H-pyrrolo[2,3-c]pyridine-5-carboxylic acid ethyl ester
Reaction equation
[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[c:6]1[c:7]([OH:26])[c:8]2[c:9]([c:10]([Br:12])[n:11]1)[n:13]([CH2:18][c:19]1[cH:20][cH:21][c:22]([F:25])[cH:23][cH:24]1)[c:14]([Br:17])[c:15]2[Br:16].[Cu:27][C:28]#[N:29]>>[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[c:6]1[c:7]([OH:26])[c:8]2[c:9]([c:10]([C:28]#[N:29])[n:11]1)[n:13]([CH2:18][c:19]1[cH:20][cH:21][c:22]([F:25])[cH:23][cH:24]1)[c:14]([Br:17])[c:15]2[Br:16]Participants
3
Sources & evidence
- ORD record
- ord-13b3cf726dea42239fea13b98f86f57d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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