Acetic acid, 2-[4-(bromomethyl)phenoxy]-, methyl ester → {4-[5-Chloro-2-(1-cyclohexylmethyl-5,6-difluoro-1H-benzoimidazol-2-yl)-phenoxymethyl]-phenoxy}-acetic acid methyl ester

HRID 201281

Reaction equation

HRID 201281 reaction equation
[CH3:27][O:28][C:29]([CH2:30][O:31][c:32]1[cH:33][cH:34][c:35]([CH2:38][Br:39])[cH:36][cH:37]1)=[O:40].[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:9]2[n:10][c:11]3[c:12]([n:13]2[CH2:14][CH:15]2[CH2:16][CH2:17][CH2:18][CH2:19][CH2:20]2)[cH:21][c:22]([F:26])[c:23]([F:25])[cH:24]3)[c:6]([OH:8])[cH:7]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:9]2[n:10][c:11]3[c:12]([n:13]2[CH2:14][CH:15]2[CH2:16][CH2:17][CH2:18][CH2:19][CH2:20]2)[cH:21][c:22]([F:26])[c:23]([F:25])[cH:24]3)[c:6]([O:8][CH2:38][c:35]2[cH:34][cH:33][c:32]([O:31][CH2:30][C:29]([O:28][CH3:27])=[O:40])[cH:37][cH:36]2)[cH:7]1

Participants

3

Reactant 2

HCID 67049717Acetic acid, 2-[4-(bromomethyl)phenoxy]-, methyl esterHCID 1363784785-chloro-2-(1-cyclohexylmethyl-5,6-difluoro-1H-benzoimidazol-2-yl)-phenol

Product 1

HCID 67050114{4-[5-Chloro-2-(1-cyclohexylmethyl-5,6-difluoro-1H-benzoimidazol-2-yl)-phenoxymethyl]-phenoxy}-acetic acid methyl ester

Sources & evidence

ORD record
ord-b51108715934446db380ecb51b03d3c6
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Linked notes

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