HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → Diethyl 5-hydroxy-1,1-dimethylpentylphosphonate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Benzenesulfonic acid, 4-methyl-, compd. with pyridine (1:1) | HCID 466102 | — |
| Reactant | Diethyl 1,1-dimethyl-5-(tetrahydropyran-2-yloxy)-5-pentylphosphonate | HCID 19689172 | — |
| Product | Diethyl 5-hydroxy-1,1-dimethylpentylphosphonate | HCID 19689221 | — |
Reaction Steps
19.9 g (0.052 mol) of diethyl 1,1-dimethyl-5-(tetrahydropyran-2-yloxy)-5-pentylphosphonate were stirred at 55° C. for 8 hours with 1.5 g (0.006 mol) of pyridinium toluene-4-sulfonate in 200 ml of aqueous ethanol. The solvent was evaporated, the residue was taken up in ethyl acetate, the solution was filtered through a silica gel column and, after evaporating the solvent, the residue was distilled in a bulb tube.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05728686 |
| Source dataset | uspto-grants-1998_03 |
| ORD ID | ord-73eb847fa4744d04af4bf241c54b60cc |
| Source note | uspto-grants-1998_03 |