HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diethyl [4-(7-benzyl-3-methylxanthin-1-yl)butyl]phosphonate → Diethyl [4-(3-methylxanthin-1-yl)butyl]phosphonate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diethyl [4-(7-benzyl-3-methylxanthin-1-yl)butyl]phosphonate | HCID 22446297 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | Diethyl [4-(3-methylxanthin-1-yl)butyl]phosphonate | HCID 22446315 | — |
Reaction Steps
15.7 g (0.035 mol) of diethyl [4-(7-benzyl-3-methylxanthin-1-yl)butyl]-phosphonate were hydrogenated in 150 ml of ethanol over 1 g of palladium (10%) on active carbon at room temperature in the course of 8 hours. The catalyst was filtered off, the filtrate was concentrated under reduced pressure and the residue was crystallized from diisopropyl ether.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05728686 |
| Source dataset | uspto-grants-1998_03 |
| ORD ID | ord-ecb037eb61a74599a6353b1d72d5a468 |
| Source note | uspto-grants-1998_03 |