Methanol → 4-bromo-N-{4-[(4-dimethylamino-quinazolin-2-ylamino)-methyl]-phenyl}-2-trifluoromethoxy-benzenesulfonamide
Reaction equation
[Br:33][c:34]1[cH:35][c:36]([O:44][C:45]([F:46])([F:47])[F:48])[c:37]([S:40](=[O:41])(=[O:42])[Cl:43])[cH:38][cH:39]1.[CH2:1]([O:2][C:3](=[O:4])[NH:10][c:11]1[cH:12][cH:13][c:14]([CH2:17][NH:18][c:19]2[n:20][c:21]3[cH:22][cH:23][cH:24][cH:25][c:26]3[c:27]([N:29]([CH3:30])[CH3:31])[n:28]2)[cH:15][cH:16]1)[c:5]1[cH:6][cH:7][cH:8][cH:9][cH:32]1.[CH3:49][OH:50].[Cl:51][CH2:52][Cl:53]>>[NH:10]([c:11]1[cH:12][cH:13][c:14]([CH2:17][NH:18][c:19]2[n:20][c:21]3[cH:22][cH:23][cH:24][cH:25][c:26]3[c:27]([N:29]([CH3:30])[CH3:31])[n:28]2)[cH:15][cH:16]1)[S:40]([c:37]1[c:36]([O:44][C:45]([F:46])([F:47])[F:48])[cH:35][c:34]([Br:33])[cH:39][cH:38]1)(=[O:41])=[O:42]Participants
5
