3-Methylimidazo(2,1-b)(1,3)thiazole-5-carboxylic acid → N-[[2-[2-amino-5-(3-fluorophenyl)-1,3-thiazole-4-carbonyl]-2-azabicyclo[3.1.0]hexan-3-yl]methyl]-3-methylimidazo[2,1-b][1,3]thiazole-5-carboxamide

HRID 203274

Reaction equation

HRID 203274 reaction equation
[CH3:24][c:25]1[n:26]2[c:27]([s:28][cH:29]1)[n:30][cH:31][c:32]2[C:33](=[O:34])[OH:35].[NH2:1][c:2]1[s:3][c:4](-[c:17]2[cH:18][c:19]([F:23])[cH:20][cH:21][cH:22]2)[c:5]([C:7](=[O:8])[N:9]2[CH:10]3[CH2:11][CH:12]3[CH2:13][CH:14]2[CH2:15][NH2:16])[n:6]1>>[NH2:1][c:2]1[s:3][c:4](-[c:17]2[cH:18][c:19]([F:23])[cH:20][cH:21][cH:22]2)[c:5]([C:7](=[O:8])[N:9]2[CH:10]3[CH2:11][CH:12]3[CH2:13][CH:14]2[CH2:15][NH:16][C:33]([c:32]2[n:26]3[c:25]([CH3:24])[cH:29][s:28][c:27]3[n:30][cH:31]2)=[O:34])[n:6]1

Participants

3

Reactant 2

HCID 212564713-Methylimidazo(2,1-b)(1,3)thiazole-5-carboxylic acidHCID 178509363HCID 178509363, compound

Product 1

HCID 178431863N-[[2-[2-amino-5-(3-fluorophenyl)-1,3-thiazole-4-carbonyl]-2-azabicyclo[3.1.0]hexan-3-yl]methyl]-3-methylimidazo[2,1-b][1,3]thiazole-5-carboxamide

Sources & evidence

ORD record
ord-e3d63ff63447425dabffc9a03446b26c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Linked notes

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