3-Chloropyridine-4-carboxylic acid → 2-[1-(3-Chloroisonicotinoyl)piperidin-4-yl]-5-(3,4-dimethoxyphenyl)-4,4-dimethyl-2,4-dihydro-3H-pyrazol-3-one
Reaction equation
[CH3:1][O:2][c:3]1[cH:4][c:5]([C:11]2=[N:15][N:14]([CH:16]3[CH2:17][CH2:18][NH:19][CH2:20][CH2:21]3)[C:13](=[O:22])[C:12]2([CH3:23])[CH3:24])[cH:6][cH:7][c:8]1[O:9][CH3:10].[Cl:25][c:26]1[c:27]([C:28](=[O:29])[OH:30])[cH:31][cH:32][n:33][cH:34]1>>[CH3:1][O:2][c:3]1[cH:4][c:5]([C:11]2=[N:15][N:14]([CH:16]3[CH2:17][CH2:18][N:19]([C:28]([c:27]4[c:26]([Cl:25])[cH:34][n:33][cH:32][cH:31]4)=[O:29])[CH2:20][CH2:21]3)[C:13](=[O:22])[C:12]2([CH3:23])[CH3:24])[cH:6][cH:7][c:8]1[O:9][CH3:10]Participants
3
Sources & evidence
- ORD record
- ord-e7623a836c924c48af0892e8b4b6fafc
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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