Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2033Generated: October 25, 2026

Diethyl (3-bromopropyl)phosphonate → Diethyl [3-(3,7-dibutylxanthin-1-yl)propyl]phosphonate

https://huagongshe.com/reaction/2033

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiethyl (3-bromopropyl)phosphonateHCID 283500—
Reactant3,7-dibutyl-2,3,6,7-tetrahydro-1H-purine-2,6-dioneHCID 350767—
ProductDiethyl [3-(3,7-dibutylxanthin-1-yl)propyl]phosphonateHCID 22446269—

Reaction Steps

The title substance was prepared from 0.02 mol of 3,7-dibutylxanthine and 0.022 mol of diethyl 3-bromopropanephosphonate analogously to Example 23 and chromatographed on silica gel (eluent: dichloromethane/methanol 20:1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05728686
Source datasetuspto-grants-1998_03
ORD IDord-850bc9b85c9e4146b22bb952817275a6
Source noteuspto-grants-1998_03