Diethyl (3-bromopropyl)phosphonate → Diethyl [7-benzyl-3-(3-methylxanthin-1-yl)propyl]phosphonate

HRID 2035

Reaction equation

HRID 2035 reaction equation
[CH2:1]([N:8]1[C:16]2[C:15](=[O:17])[NH:14][C:13](=[O:18])[N:12]([CH3:19])[C:11]=2[N:10]=[CH:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.Br[CH2:21][CH2:22][CH2:23][P:24]([O:29][CH2:30][CH3:31])(=[O:28])[O:25][CH2:26][CH3:27]>>[CH2:1]([N:8]1[C:16]2[C:15](=[O:17])[N:14]([CH2:21][CH2:22][CH2:23][P:24](=[O:28])([O:29][CH2:30][CH3:31])[O:25][CH2:26][CH3:27])[C:13](=[O:18])[N:12]([CH3:19])[C:11]=2[N:10]=[CH:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 283500Diethyl (3-bromopropyl)phosphonateHCID 6856307-Benzyl-3-methylxanthine

Product 1

HCID 22446272Diethyl [7-benzyl-3-(3-methylxanthin-1-yl)propyl]phosphonate

Procedure

The title substance was prepared from 7-benzyl-3-methylxanthine, (0.04 mol) and diethyl 3-bromopropanphosphonate (0.046 mol) analogously to Example 23.

Sources & evidence

ORD record
ord-8db1122947c440319b376bdd83c6820e
Source dataset
uspto-grants-1998_03
Patent number
US05728686

Linked notes

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