7-Benzyl-3-methylxanthine → Diethyl [5-(7-benzyl-3-methylxanthin-1-yl)pentyl]phosphonate

HRID 2036

Reaction equation

HRID 2036 reaction equation
[CH2:1]([N:8]1[C:16]2[C:15](=[O:17])[NH:14][C:13](=[O:18])[N:12]([CH3:19])[C:11]=2[N:10]=[CH:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.Br[CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][P:26]([O:31][CH2:32][CH3:33])(=[O:30])[O:27][CH2:28][CH3:29]>>[CH2:1]([N:8]1[C:16]2[C:15](=[O:17])[N:14]([CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][P:26](=[O:30])([O:31][CH2:32][CH3:33])[O:27][CH2:28][CH3:29])[C:13](=[O:18])[N:12]([CH3:19])[C:11]=2[N:10]=[CH:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 6856307-Benzyl-3-methylxanthineHCID 10924159Diethyl-5-bromopentylphosphonate

Product 1

HCID 22446305Diethyl [5-(7-benzyl-3-methylxanthin-1-yl)pentyl]phosphonate

Procedure

The title compound was prepared from 7-benzyl-3-methylxanthine (0.059 mol) and diethyl 5-bromopentanephosphonate (0.07 mol) analogously to Example 23.

Sources & evidence

ORD record
ord-dbd5f59d9f5c45dc83584e93fb652d29
Source dataset
uspto-grants-1998_03
Patent number
US05728686

Linked notes

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