1-(2-Bromoacetyl)pyrrolidine-2-carbonitrile → Ethyl 4-[[2-(2-cyanopyrrolidin-1-yl)-2-oxoethyl]amino]bicyclo[2.2.1]heptane-1-carboxylate

HRID 203750Notes

Reaction equation

HRID 203750 reaction equation
[Br:14][CH2:15][C:16](=[O:17])[N:18]1[CH:19]([C:23]#[N:24])[CH2:20][CH2:21][CH2:22]1.[NH2:1][C:2]12[CH2:3][CH2:4][C:5]([C:9](=[O:10])[O:11][CH2:12][CH3:13])([CH2:6][CH2:7]1)[CH2:8]2>>[NH:1]([C:2]12[CH2:3][CH2:4][C:5]([C:9](=[O:10])[O:11][CH2:12][CH3:13])([CH2:6][CH2:7]1)[CH2:8]2)[CH2:15][C:16](=[O:17])[N:18]1[CH:19]([C:23]#[N:24])[CH2:20][CH2:21][CH2:22]1

Participants

3

Reactant 2

HCID 178609191-(2-Bromoacetyl)pyrrolidine-2-carbonitrileHCID 23149671Ethyl 4-aminobicyclo[2.2.1]heptane-1-carboxylate

Product 1

HCID 23149676Ethyl 4-[[2-(2-cyanopyrrolidin-1-yl)-2-oxoethyl]amino]bicyclo[2.2.1]heptane-1-carboxylate

Sources & evidence

ORD record
ord-99509067f8f94e299467c142e620cced
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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