Cyclopropylamine → 6-bromo-N-cyclopropylpyridine-3-carboxamide

HRID 2037789Notes

Reaction equation

[Br:1][C:2]1[CH:10]=[CH:9][C:5]([C:6](Cl)=[O:7])=[CH:4][N:3]=1.[CH:11]1([NH2:14])[CH2:13][CH2:12]1>>[Br:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([NH:14][CH:11]2[CH2:13][CH2:12]2)=[O:7])=[CH:4][N:3]=1

Participants

Reactant 2

HCID 69828Cyclopropylamine

HCID 234995286-Bromonicotinoyl chloride

Product 1

HCID 658091726-bromo-N-cyclopropylpyridine-3-carboxamide

Procedure

6-bromo-N-cyclopropylnicotinamide was prepared from 6-bromonicotinoyl chloride and cyclopropylamine.

Sources & evidence

ORD record: ord-67f04bbe4a724c01a8175db371349d1d
Source dataset: uspto-grants-2013_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08575156B2

Reaction notes

Loading…