1-(3,3-Diethoxyprop-1-yn-1-yl)-3-methylbenzene → 3-(m-Tolyl)propiolaldehyde
Reaction equation
ClC1C=C(C#CC=O)C=CC=1.C([O:14][CH:15](OCC)[C:16]#[C:17][C:18]1[CH:23]=[CH:22][CH:21]=[C:20]([CH3:24])[CH:19]=1)C>>[CH3:24][C:20]1[CH:19]=[C:18]([C:17]#[C:16][CH:15]=[O:14])[CH:23]=[CH:22][CH:21]=1Participants
3
Procedure
The title compound was synthesized following the procedure reported for Compound 31d, but starting from Compound 91a instead of Compound 31c. The crude title compound was used in the next step without further purification.
Workup
- customThe crude title compound was used in the next step without further purification
Sources & evidence
- ORD record
- ord-0ac243aaa1b841659bffd022b0fab313
- Source dataset
- uspto-grants-2013_11
- Patent number
- US08580962B2
Reaction notes
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