4-Chloro-6,7-dimethoxyquinazoline → 4-(5-Benzyloxy-2,3-dihydro-indol-1-yl)-6,7-dimethoxy-quinazoline

HRID 204344

Reaction equation

HRID 204344 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[cH:10][c:11]2[c:15]([cH:16][cH:17]1)[NH:14][CH2:13][CH2:12]2.[Cl:18][c:19]1[n:20][cH:21][n:22][c:23]2[cH:24][c:25]([O:31][CH3:32])[c:26]([O:29][CH3:30])[cH:27][c:28]12>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[cH:10][c:11]2[c:15]([cH:16][cH:17]1)[N:14]([c:19]1[n:20][cH:21][n:22][c:23]3[cH:24][c:25]([O:31][CH3:32])[c:26]([O:29][CH3:30])[cH:27][c:28]13)[CH2:13][CH2:12]2

Participants

3

Reactant 2

HCID 27693644-Chloro-6,7-dimethoxyquinazolineHCID 167948815-(Benzyloxy)-2,3-dihydro-1H-indole

Product 1

HCID 189328044-(5-Benzyloxy-2,3-dihydro-indol-1-yl)-6,7-dimethoxy-quinazoline

Sources & evidence

ORD record
ord-4abbe2f424c74748a99ca7aabaf717a0
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Linked notes

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