Phosphine oxide, (chloromethyl)dimethyl- → HCID 19689166, compound

HRID 2045

Reaction equation

HRID 2045 reaction equation
[Na].[CH2:2]([N:8]1[C:17](=[O:18])[C:16]2[NH:15][CH:14]=[N:13][C:12]=2[N:11]([CH3:19])[C:9]1=[O:10])[CH2:3][CH2:4][CH2:5][CH2:6][CH3:7].Cl[CH2:21][P:22](=[O:25])([CH3:24])[CH3:23]>>[CH2:2]([N:8]1[C:17](=[O:18])[C:16]2[N:15]([CH2:21][P:22](=[O:25])([CH3:24])[CH3:23])[CH:14]=[N:13][C:12]=2[N:11]([CH3:19])[C:9]1=[O:10])[CH2:3][CH2:4][CH2:5][CH2:6][CH3:7]

Participants

3

Reactant 2

HCID 74224Phosphine oxide, (chloromethyl)dimethyl-HCID 67653472HCID 67653472, compound

Product 1

HCID 19689166HCID 19689166, compound

Procedure

The title substance was prepared from 26 g (0.1 mol) of 1-hexyl-3-methylxanthine sodium salt and chloromethyldimethylphosphine oxide analogously to Example 59 and crystallized from hexane.

Workup

  1. customcrystallized from hexane

Sources & evidence

ORD record
ord-ef1db8c6e55e47b682289c4e57d4ed22
Source dataset
uspto-grants-1998_03
Patent number
US05728686

Linked notes

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