4-Octyloxybenzoyl chloride → HCID 14513177, compound

Reaction equation

[CH3:1][O:2][CH:3]([C:5]1[CH:10]=[CH:9][C:8]([OH:11])=[CH:7][CH:6]=1)[CH3:4].[CH2:12]([O:20][C:21]1[CH:29]=[CH:28][C:24]([C:25](Cl)=[O:26])=[CH:23][CH:22]=1)[CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH3:19]>>[CH2:12]([O:20][C:21]1[CH:22]=[CH:23][C:24]([C:25]([O:11][C:8]2[CH:9]=[CH:10][C:5]([CH:3]([O:2][CH3:1])[CH3:4])=[CH:6][CH:7]=2)=[O:26])=[CH:28][CH:29]=1)[CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH3:19]

Participants

Reactant 2

HCID 27602504-Octyloxybenzoyl chloride

HCID 133794894-(1-Methoxyethyl)phenol

Product 1

HCID 14513177HCID 14513177, compound

Procedure

The procedure of Example 26 was followed except for use of (-)-4-(1-methoxyethyl)phenol in place of (+)-4-(1-methoxyethyl)phenol and 4-octyloxybenzoic acid chloride in place of 4'-octyloxy-4-biphenylcarboxylic acid chloride to obtain (-)-4-(1-methoxyethyl)phenyl 4-octyloxybenzoate. [α]D20 =-57.5° (c=1, CHCl3).

Sources & evidence

ORD record: ord-7738a7234b27405796a87a26c720ef44
Source dataset: uspto-grants-1991_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05013479

Reaction notes

Loading…