2,6-Dichloro-isonicotinoyl chloride → ethyl N-(2,6-dichloroisonicotinoyl)-5,7-dihydro-6H-dibenz[c,e]azepine-6-carboximidate

HRID 2050836Notes

Reaction equation

HRID 2050836 reaction equation
[CH:1]1[C:11]2[C:10]3[CH:12]=[CH:13][CH:14]=[CH:15][C:9]=3[CH2:8][N:7]([C:16](=[NH:20])[O:17][CH2:18][CH3:19])[CH2:6][C:5]=2[CH:4]=[CH:3][CH:2]=1.[Cl:21][C:22]1[CH:27]=[C:26]([C:28](Cl)=[O:29])[CH:25]=[C:24]([Cl:31])[N:23]=1>>[Cl:21][C:22]1[CH:27]=[C:26]([CH:25]=[C:24]([Cl:31])[N:23]=1)[C:28]([N:20]=[C:16]([N:7]1[CH2:6][C:5]2[CH:4]=[CH:3][CH:2]=[CH:1][C:11]=2[C:10]2[CH:12]=[CH:13][CH:14]=[CH:15][C:9]=2[CH2:8]1)[O:17][CH2:18][CH3:19])=[O:29]

Participants

3

Reactant 2

HCID 27816432,6-Dichloro-isonicotinoyl chlorideHCID 19833914ethyl 5,7-dihydro-6H-dibenz[c,e]azepine-6carboximidate

Product 1

HCID 19833902ethyl N-(2,6-dichloroisonicotinoyl)-5,7-dihydro-6H-dibenz[c,e]azepine-6-carboximidate

Procedure

starting from ethyl 5,7-dihydro-6H-dibenz[c,e]azepine-6-carboximidate and 2,6-dichloropyridine-4-carboxylic acid chloride, there is obtained ethyl N-(2,6-dichloroisonicotinoyl)-5,7-dihydro-6H-dibenz[c,e]azepine-6-carboximidate, m.p. 151°-152° C.;

Sources & evidence

ORD record
ord-de61f138763343078da55930626d73f1
Source dataset
uspto-grants-1991_05
Patent number
US05015640

Reaction notes

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