Acetophenone → 1,1-Dicyano-2-phenyl-2-(1-bromoethyl)ethylene
Reaction equation
[Br:1]Br.[C:3]1([C:9](=[C:12]([C:15]#[N:16])[C:13]#[N:14])[CH2:10][CH3:11])[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1.C(C1C=CC=CC=1)(=O)C>C1C=CC=CC=1>[Br:1][CH:10]([CH3:11])[C:9](=[C:12]([C:13]#[N:14])[C:15]#[N:16])[C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1Participants
5
Reactant 3
Product 1
Reagents, catalysts & solvents 1
Procedure
2.7 ml of bromine are added to 9.1 g of 1-phenylpropylidene-propanedinitrile and 0.2 g of acetophenone in 100 ml of benzene and the mixture is stirred at room temperature for 1.5 hours. The residue obtained after evaporation under vacuum is recrystallised from 25 ml of ethanol. 11,7 g of 2-bromo-1-phenyl-propylidene-propanedinitrile melting at 103° to 104° C. are obtained.
Workup
- customThe residue obtained
- customafter evaporation under vacuum
- customis recrystallised from 25 ml of ethanol
Sources & evidence
- ORD record
- ord-fb50268784624b5191d084c34fb33e27
- Source dataset
- uspto-grants-1980_01
- Patent number
- US04186012
Reaction notes
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