Phosphine oxide, (chloromethyl)dimethyl- → HCID 19689189, compound

HRID 2053

Reaction equation

HRID 2053 reaction equation
[CH2:1]([N:8]1[C:16]2[C:15](=[O:17])[NH:14][C:13](=[O:18])[N:12]([C:19]3[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=3)[C:11]=2[N:10]=[CH:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.Cl[CH2:26][P:27](=[O:30])([CH3:29])[CH3:28]>>[CH2:1]([N:8]1[C:16]2[C:15](=[O:17])[N:14]([CH2:26][P:27](=[O:30])([CH3:29])[CH3:28])[C:13](=[O:18])[N:12]([C:19]3[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=3)[C:11]=2[N:10]=[CH:9]1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

3

Procedure

The title substance was prepared from 6.5 g (0.02 mol) of 7-benzyl-3-phenylxanthine and 3.1 g (0.0245 mol) of chloromethyldimethylphosphine oxide analogously to Example 67.

Sources & evidence

ORD record
ord-bdd1e9efc45840ebb2811f3be6d3fe5f
Source dataset
uspto-grants-1998_03
Patent number
US05728686

Linked notes

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