2-Amino-5-chlorobenzophenone → HCID 11189100, compound
Reaction equation
[CH2:1]([N:8]1[CH:12]=[CH:11][N:10]=[C:9]1[CH2:13][C:14]([OH:16])=O)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[NH2:17][C:18]1[CH:23]=[CH:22][C:21]([Cl:24])=[CH:20][C:19]=1[C:25]([C:27]1[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=1)=O>>[CH2:1]([N:8]1[CH:12]=[CH:11][N:10]=[C:9]1[C:13]1[C:14](=[O:16])[NH:17][C:18]2[C:19]([C:25]=1[C:27]1[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=1)=[CH:20][C:21]([Cl:24])=[CH:22][CH:23]=2)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1Participants
3
Procedure
Synthesized from (1-benzyl-1H-imidazol-2-yl)-acetic acid (Tetrahedron Letters, 37 (51), 9259, 1996) and (2-amino-5-chloro-phenyl)-phenyl-methanone according to general procedure 2. Yield 43%.
Sources & evidence
- ORD record
- ord-5001c2877715427f8fe0205ff6c171f7
- Source dataset
- uspto-grants-2008_02
- Patent number
- US07326788B2