1-Butanol → 9-[(4-fluorophenyl)methyl]-N-[1-[2-(2-pyridinyl)ethyl]-4-piperidinyl]-9H-purin-8-amine

HRID 205645

Reaction equation

HRID 205645 reaction equation
[CH2:33]([OH:34])[CH2:35][CH2:36][CH3:37].[CH:1](=[CH2:2])[c:3]1[n:4][cH:5][cH:6][cH:7][cH:8]1.[F:9][c:10]1[cH:11][cH:12][c:13]([CH2:16][n:17]2[c:18]3[n:19][cH:20][n:21][cH:22][c:23]3[n:24][c:25]2[NH:26][CH:27]2[CH2:28][CH2:29][NH:30][CH2:31][CH2:32]2)[cH:14][cH:15]1>>[CH2:1]([CH2:2][N:30]1[CH2:29][CH2:28][CH:27]([NH:26][c:25]2[n:17]([CH2:16][c:13]3[cH:12][cH:11][c:10]([F:9])[cH:15][cH:14]3)[c:18]3[n:19][cH:20][n:21][cH:22][c:23]3[n:24]2)[CH2:32][CH2:31]1)[c:3]1[n:4][cH:5][cH:6][cH:7][cH:8]1

Participants

4

Reactant 3

HCID 2631-ButanolHCID 75212-VinylpyridineHCID 197853439-[(4-fluorophenyl)methyl]-N-(4-piperidinyl)-9H-purin-8-amine

Product 1

HCID 197853169-[(4-fluorophenyl)methyl]-N-[1-[2-(2-pyridinyl)ethyl]-4-piperidinyl]-9H-purin-8-amine

Sources & evidence

ORD record
ord-ce8ed02432b444a194192363972fa89e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Linked notes

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