Propionate ion → 2-(Isoquinolin-5-yl)-2-methylpropanoic acid

HRID 2056934

Reaction equation

[CH:1]1[C:10]2[C:5](=[C:6]([C:11]([CH3:18])([CH3:17])[C:12]([O:14]CC)=[O:13])[CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][N:2]=1.C([O-])(=O)CC>>[CH:1]1[C:10]2[C:5](=[C:6]([C:11]([CH3:18])([CH3:17])[C:12]([OH:14])=[O:13])[CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][N:2]=1

Participants

Reactant 2

HCID 104745Propionate ion

HCID 22032678Ethyl 2-(5-isoquinolinyl)-2-methylpropanoate

Product 1

HCID 223376132-(Isoquinolin-5-yl)-2-methylpropanoic acid

Procedure

The title compound was prepared using the procedure described in Example 249A using ethyl 2-(5-isoquinolinyl)-2-methylpropanoate instead of ethyl 2-5-isoquinolinyl)propanoate.

Sources & evidence

ORD record: ord-58e04315553a4158a0a788d5837a7f8b
Source dataset: uspto-grants-2008_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07335678B2

Linked notes

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