Safrole → Safrole oxide

HRID 2057692

Reaction equation

HRID 2057692 reaction equation
[CH2:1]([C:4]1[CH:12]=[CH:11][C:7]2[O:8][CH2:9][O:10][C:6]=2[CH:5]=1)[CH:2]=[CH2:3].CCC(OO)=[O:16]>CCC(Cl)Cl>[O:16]1[CH2:3][CH:2]1[CH2:1][C:4]1[CH:12]=[CH:11][C:7]2[O:8][CH2:9][O:10][C:6]=2[CH:5]=1

Participants

4

Reactant 2

HCID 5144SafroleHCID 65136Perpropionic acid

Product 1

HCID 101123Safrole oxide

Reagents, catalysts & solvents 1

HCID 65731,1-DichloropropaneSolvent

Procedure

48.82 g (0.3 mol) of 5-(2-propenyl)-1,3-benzodioxole were reacted with 45 g (0.1 mol) of a 20% strength solution of perpropionic acid in dichloropropane at 30° C. as described in Example 1. After a reaction time of 6 hours, the peracid conversion was 96%. 5-(Oxiranylmethyl)-1,3-benzodioxole was formed with a selectivity of 68%.

Workup

  1. customAfter a reaction time of 6 hours

Sources & evidence

ORD record
ord-0e6bb625f7d6498f99187530cf82f287
Source dataset
uspto-grants-1980_07
Patent number
US04212809

Linked notes

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