Succinic Acid → 1-Cyclooctylmethylimidazole hydrogen succinate

HRID 2058448Notes

Reaction equation

HRID 2058448 reaction equation
[C:1]([OH:8])(=[O:7])[CH2:2][CH2:3][C:4]([OH:6])=[O:5].[CH:9]1([CH2:17][N:18]2[CH:22]=[CH:21][N:20]=[CH:19]2)[CH2:16][CH2:15][CH2:14][CH2:13][CH2:12][CH2:11][CH2:10]1>C(O)C>[C:1]([OH:8])(=[O:7])[CH2:2][CH2:3][C:4]([OH:6])=[O:5].[CH:9]1([CH2:17][N:18]2[CH:22]=[CH:21][N:20]=[CH:19]2)[CH2:16][CH2:15][CH2:14][CH2:13][CH2:12][CH2:11][CH2:10]1

Participants

4

Reactant 2

HCID 1110Succinic AcidHCID 205502381-Cyclooctylmethylimidazole

Product 1

HCID 205502501-Cyclooctylmethylimidazole hydrogen succinateYield 44.7%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent2×

Procedure

A solution of succinic acid (0.23 g) in ethanol (~5 ml) was added to a solution of 1-cyclooctylmethylimidazole (0.38 g) in ethanol (5 ml). Evaporation of the solution afforded a white solid. Recrystallisation of the solid from ethyl acetate afforded 1-cyclooctylmethylimidazole hydrogen succinate (0.27 g) as colourless plates, m.p. 86° to 87° C.

Workup

  1. customEvaporation of the solution
  2. customafforded a white solid
  3. customRecrystallisation of the solid from ethyl acetate

Sources & evidence

ORD record
ord-f3c8a4fd58044f61b41eedb23a9e3b99
Source dataset
uspto-grants-1982_03
Patent number
US04317830

Reaction notes

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