Acetic Anhydride → HCID 178475112, compound

Reaction equation

[OH:1][C:2]1[C:3]([C:8]([NH2:10])=[O:9])=[N:4][CH:5]=[CH:6][N:7]=1.[C:11](OC(=O)C)(=[O:13])[CH3:12]>>[C:11]([NH:10][C:8]([C:3]1[C:2]([OH:1])=[N:7][CH:6]=[CH:5][N:4]=1)=[O:9])(=[O:13])[CH3:12]

Participants

Reactant 2

HCID 7918Acetic Anhydride

HCID 178513804HCID 178513804, compound

Product 1

HCID 178475112HCID 178475112, compound

Conditions

Temperature: 110 °C

Procedure

In 5 mL of acetic anhydride is suspended 0.5 g of 3-hydroxy-2-pyrazinecarboxamide. The resulting solution is stirred at 110° C. for 1 hour. The deposited crystals are collected by filtration to obtain 0.5 g of N2-acetyl-3-hydroxy-2-pyrazinecarboxamide.

Workup

filtrationThe deposited crystals are collected by filtration

Sources & evidence

ORD record: ord-a5748179c64349858a0b6408d0b889f4
Source dataset: uspto-grants-2012_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: USRE043748E1

Reaction notes

Loading…