Cyclopropylmethyl methanesulfonate → HCID 60911320, compound

Reaction equation

[NH2:1][C:2]1[N:6]=[CH:5][NH:4][N:3]=1.[CH:7]1([CH2:10]OS(C)(=O)=O)[CH2:9][CH2:8]1>>[CH:7]1([CH2:10][N:4]2[CH:5]=[N:6][C:2]([NH2:1])=[N:3]2)[CH2:9][CH2:8]1

Participants

Reactant 2

HCID 135444Cyclopropylmethyl methanesulfonate

HCID 178418311HCID 178418311, compound

Product 1

HCID 60911320HCID 60911320, compound

Procedure

Prepared in analogy to example 3a) starting with 3-amino-1,2,4-triazole and methanesulfonic acid cyclopropylmethyl ester (Journal of the American Chemical Society 128, 3118 (2006)). The title compound was obtained as a brownish solid (Yield=25%). MS ISP (m/e): 138.1 (100) [M+].

Workup

customPrepared in analogy to example 3a)

Sources & evidence

ORD record: ord-e5494ec18c3a47b9a36ca3e36441a0c7
Source dataset: uspto-grants-2012_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08288403B2

Reaction notes

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